Rizzoli & Isles

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament — she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

• 
  Angie Harmon

  Detective Jane Rizzoli
• 
  Sasha Alexander

  Dr. Maura Isles
• 
  Jordan Bridges

  Frankie Rizzoli Jr.
• 
  Bruce McGill

  Detective Vince Korsak
• 
  Lorraine Bracco

  Angela Rizzoli
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  Idara Victor

  Nina Holiday
• 
  Adam Sinclair

  Kent Drake